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Keanu Reeves and Alex Winter, who co-starred in the sci-fi comedy franchise of the same name, are reuniting for a Broadway production of Samuel Beckett's 1950s play “Waiting for Godot.”

Reeves is set to play Estragon, while Winter will portray Vladimir in the Jamie Lloyd-directed tragicomedy, according to a Thursday press release.

“We’re incredibly excited to be on stage together and work with the great Jamie Lloyd in one of our favorite plays,” the actors said in a joint statement.

Lloyd, a British theater director, gushed about Reeves and Winter’s seamless dynamic in an interview with The New York Times published Thursday.

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“Their instant chemistry and their shorthand and their friendship is going to be so valuable,” Lloyd said. “This is a very deeply complex play, as we all know, but it’s also a very funny play, and they’re very witty people and their shared sense of humor in those movies and in real life is going to be very beneficial to the production.”

“Waiting for Godot” will premiere in fall 2025. The play’s venue has not been announced.

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In the cult favorite “Bill & Ted” trilogy, Winter and Reeves play metalhead slouches Bill Preston and Ted Logan, respectively. The franchise debuted with 1989’s “Bill & Ted's Excellent Adventure,” which grossed $40.5 million at the global box office.

Reeves and Winter reprised their roles for sequels “Bill & Ted’s Bogus Journey” (1991) and “Bill & Ted Face the Music” (2020), the latter of which earned a People’s Choice Awards nomination for favorite comedy movie.